10 Best OTC Phentermine Alternatives (Adipex) Without Prescription (2023)

Table of Contents
Phentermine Over The Counter: Top 10 Natural Alternatives to Adipex Weight Loss Pills Review of the Top Natural Phentermine Alternatives of 2023 #1. PhenQ: Best Phentermine Alternative for Weight Loss #2. Phen24: Great Alternative to Adipex for Nighttime Fat Burning #3. PrimeShred: Good Phentermine Substitute for Energy and Appetite Suppression #4. Leanbean: Natural Diet Pills Available Without a Prescription #5. PhenGold: Recommended OTC Adipex Alternative to Lose Weight Quickly What Is Phentermine? How We Ranked the Top OTC Phentermine Alternatives Quality Ingredients Dosage Customer Reviews Safety Price Product Guarantee Benefits of Choosing a Natural Alternative to Phentermine Diet Pills No Prescription Necessary Effective Weight Loss Solution Milder Side Effects Natural Ingredients Health Benefits Risks and Side Effects of Prescription Phentermine Pills Common Ingredients Found in OTC Weight Loss Supplements Alpha-Lipoic Acid Caffeine Capsimax L-Carnitine Chromium Green Tea Guarana Extract Cayenne Pepper Green Coffee Where to Buy Real Phentermine (Adipex-P) How Long Does It Take for Natural Diet Pills to Help You Lose Weight? Things To Consider Before You Buy an OTC Phentermine Alternative Frequently Asked Questions on Phentermine Replacements How long can you take phentermine? How much weight can you lose on phentermine in 3 months? Is Phentermine a prescription drug? Who should not use phentermine weight loss pills? How much do diet pills like phentermine cost? Summary of the Top Recommended Alternatives to Phentermine Weight Loss Pills FAQs Videos References

* Please contact your primary care provider to be sure these supplements are right for you.

Phentermine, also known as Adipex, is a prescription weight loss medication that’s used to suppress appetite. However, phentermine can potentially have adverse side effects, including dry mouth and anxiety.

Fortunately, there are various natural alternatives to phentermine available on the market. These natural OTC phentermine alternatives are designed to offer similar results to prescription phentermine pills but without the same harmful effects.

The best OTC phentermine substitutes can help accelerate your weight loss journey by suppressing appetite, burning stubborn fat, boosting your metabolism, and increasing energy levels. And best of all? The weight loss results are achieved using cnatural ingredients.

This guide looks at the best phentermine over-the-counter alternatives to support your weight loss goals.

Phentermine Over The Counter: Top 10 Natural Alternatives to Adipex Weight Loss Pills

  • PhenQ: Best OTC phentermine alternative overall
  • Phen24: Great metabolism booster for 24-hour fat burning
  • PrimeShred: Good men’s diet pills for burning fat
  • Leanbean: Best adipex alternative for women
  • PhenGold: Best alternative to anti-obesity medication
  • Instant Knockout: Recommended for belly fat
  • PhenQ PM: Highest quality nighttime fat burner
  • Trimtone: Top-notch diet pills for women over 50
  • CalmLean: Best stimulant-free fat burner for men
  • Keto Charge: Best for keto diet and intermittent fasting

Review of the Top Natural Phentermine Alternatives of 2023

#1. PhenQ: Best Phentermine Alternative for Weight Loss

10 Best OTC Phentermine Alternatives (Adipex) Without Prescription (1)

PhenQ, a supplement by Wolfson Berg Limited, is one of the best OTC diet pills available to support your diet and exercise efforts. The product has a similar effect on the body as phentermine, and it targets several physiological processes to help you lose weight, including appetite suppression. This phentermine alternative has an organic formula and contains no dairy or gluten, making it a viable option for allergy sufferers.

You need to take one PhenQ tablet with breakfast and one with lunch. You can expect results within a few weeks after taking this weight loss pill. Those who take these dietary supplements for three months or longer tend to see optimal results.

PhenQ comes with a 60-day money-back guarantee.

The Benefits of Taking PhenQ

As one of the best phentermine alternatives, PhenQ offers the following benefits:

Appetite suppression: PhenQ can suppress hunger and sugar cravings, preventing weight gain due to binge eating.

Metabolism rate increase: The formula contains ingredients which can boost your insulin production and accelerate weight loss.

Energy level boost: The alpha-lipoic acid and caffeine in the formula can give you the energy you need for effective workouts while enhancing your mood.

Stored fat loss: PhenQ can help your body extract energy from your stored fat, aiding in weight loss.

How PhenQ Works – Formula Overview

The PhenQ formula combines clinically proven ingredients to promote metabolic health and help your body burn fat. Some of these vegetarian ingredients include:

  • α-Lacys Reset®
  • L-carnitine fumarate
  • Capsimax powder
  • Caffeine anhydrous
  • Chromium picolinate
  • Opuntia vulgaris

L-carnitine fumarate is a synthetic amino acid that can promote fat metabolism to give you a long-lasting energy boost while promoting weight loss. This ingredient works with α-Lacys Reset®, an alpha-lipoic acid that can trigger thermogenesis, improving your workout results while burning body fat.

The chromium picolinate can suppress your sugar cravings and help your body regulate sugar levels, reducing your risk of insulin resistance and type 2 diabetes.

Who Is This Weight Loss Supplement Best For?

PhenQ is one of the top phentermine alternatives and a viable option for all people who want to lose weight. This natural phentermine alternative can support up to five metabolic processes to help you lose weight and improve the results of vigorous exercise.

Whether you are sensitive to gluten or lactose intolerant, PhenQ is the weight loss pill for you. If you suffer from chronic fatigue, consider PhenQ to energize your body and improve your focus.

Click Here for the Lowest Price on PhenQ

#2. Phen24: Great Alternative to Adipex for Nighttime Fat Burning

10 Best OTC Phentermine Alternatives (Adipex) Without Prescription (2)

Phen24 is a natural OTC phentermine alternative with a unique formula designed to help you burn fat throughout the night and day. The daytime supplement features a natural appetite suppressant and ingredients that can help you burn calories. The nighttime dietary supplement can keep sugar cravings at bay and promotes fat-burning processes without affecting sleep quality.

The recommended dosage of Phen24 is three tablets per day. You should take one daytime pill with breakfast and two nighttime pills fifteen minutes after dinner. Each bottle contains a month’s supply: 30 daytime diet pills and 60 nighttime pills.

Phen24 comes with a 60-day money-back guarantee.

The Benefits of Taking Phen24

Phen24 offers a wide range of benefits as one of the best phentermine alternatives to reduce calories:

Healthy calorie intake: Phen24 is a supplement that effectively suppresses appetite. If your weight gain is due to overeating, these natural supplements can help you maintain a healthy dietary intake.

Thermogenesis support: The Phen24 formula can promote thermogenesis, the metabolic process of burning calories to generate heat.

Energy level increase: The daytime formula can increase your energy levels, making it easier for you to move around, exercise, and get rid of extra calories.

Quality sleep: Even though Phen24 promotes 24/7 fat burning, it promises not to make you jittery or keep you up at night.

How Phen24 Works – Formula Overview

The Phen24 daytime formula contains the following natural ingredients:

  • Zinc
  • Manganese
  • Copper
  • Iodine
  • Caffeine
  • Guarana extract
  • L-phenylalanine
  • Cayenne pepper

The nighttime formula consists of:

  • Ascorbic acid (Vitamin C)
  • Calcium D-pantothenate
  • Pyridoxine HCL (Vitamin B6)
  • D-biotin
  • Chromium
  • Molybdenum
  • Glucomannan
  • Green tea extract
  • Hops extract

The daytime formula’s ingredients, such as caffeine, guarana extract, and manganese, can keep your energy levels up and help you stay mentally alert. The fat-burning ingredients in this formula include zinc, copper, and cayenne pepper. L-phenylalanine, an amino acid, is also an appetite suppressant.

In the nighttime formula, Vitamin B6, D-biotin, and tea extract can improve metabolism and fat-burning processes. Chromium and glucomannan are used as natural appetite suppressants, and the hops extract is included to improve sleep quality.

(Video) Best Weight Loss Pills with SIGNIFICANT WEIGHT LOSS (better than phentermine) SugarMD

Who Is This Weight Loss Supplement Best For?

Phen24 is the best over-the-counter phentermine alternative for people who want to curb food cravings, burn more calories, and sleep better at night. With ingredients such as molybdenum and vitamin C, Phen24 is designed to promote your overall well-being.

Click Here for the Lowest Price on Phen24

#3. PrimeShred: Good Phentermine Substitute for Energy and Appetite Suppression

10 Best OTC Phentermine Alternatives (Adipex) Without Prescription (3)

PrimeShred is a popular weight loss supplement that is designed to support muscle mass development. This over-the-counter phentermine alternative is advertised as free of potentially harmful compounds, such as preservatives and artificial sweeteners. PrimeShred also contains no gluten, soy, GMOs, or dairy.

For best results, you should take three PrimeShred tablets around 20 minutes before breakfast daily.

PrimeShred comes with a 100-day money-back guarantee.

The Benefits of Taking PrimeShred

PrimeShred is one of the best phentermine alternatives for muscle development and offers the following benefits:

Optimal hormone and metabolism regulation: The PrimeShred ingredients can regulate fat-burning hormones, including thyroid gland hormones.

Faster weight loss: The metabolism-boosting formula can allow you to lose weight quickly. Combine these phentermine alternative supplements with regular exercise and a balanced diet and you can expect to see noticeable results in weeks.

Muscle health development: Ingredients such as L-theanine can promote oxygen-rich blood flow to muscle tissue. The results often include faster muscle healing and more energy during workouts.

Energy boost: The PrimeShred formula is rich in minerals and vitamins included in the supplement to enhance your mental health and energize you throughout the day.

How PrimeShred Works – Formula Overview

PrimeShred contains the following all-natural ingredients:

  • Vitamins B3, B6, and B12
  • Green tea extract
  • Green coffee bean extract
  • L-tyrosine
  • Rhodiola rosea root
  • L-theanine
  • Caffeine anhydrous
  • Cayenne pepper
  • Dimethylaminoethanol (DMAE)
  • BioPerine® black pepper

Rhodiola rosea root can activate one of the fat-burning enzymes, hormone-sensitive lipase, which can lower the body’s triglyceride levels, reducing body fat. L-theanine and Rhodiola rosea root are the two ingredients responsible for muscle growth, and they can facilitate the supply of oxygen and nutrients to the muscles during physical activity.

The ingredients responsible for metabolism regulation and fat burning include tea extract, L-tyrosine, caffeine anhydrous, and cayenne pepper. Green coffee bean extract also is known to have significant weight loss properties, and it can reduce lethargy and fatigue, keeping you alert for several hours after taking the tablets.

B vitamins are integral in promoting overall health and well-being. These ingredients can increase your energy levels and brain function, and they can enhance cell metabolism, which aids in weight loss.

Who Is This Weight Loss Supplement Best For?

PrimeShred is the ideal weight loss supplement for men and women with high-intensity exercise routines.

These pills are also suitable if you must address a combination of thinning muscle mass and unhealthy weight gain. If you suffer from muscle atrophy due to misuse, genetics, lacking nutrition, or an underlying health condition, these phentermine over-the-counter alternatives might be a viable option.

Does your muscle atrophy result from a health concern? Consult with your doctor before taking PrimeShred.

Click Here for the Lowest Price on PrimeShred

#4. Leanbean: Natural Diet Pills Available Without a Prescription

10 Best OTC Phentermine Alternatives (Adipex) Without Prescription (4)

Leanbean is among the best over-the-counter diet pills for women and a high-quality alternative to phentermine prescription medication. This all-natural formula is compatible with female physiology and can promote healthy hormone production.

These phentermine over-the-counter alternatives promote 24/7 fat burning, and you must take six pills at regular intervals throughout the day. To achieve optimal results, combine this product with proper diet and exercise.

Leanbean comes with a 90-day money-back guarantee.

The Benefits of Taking Leanbean

As one of the best natural phentermine alternatives for women, Leanbean offers several health benefits:

Suppresses food cravings: Taking Leanbean can make you feel full, eliminating the temptation to help yourself to unhealthy foods.

Promotes fat metabolism: The all-natural ingredients in Leanbean can speed up your metabolism, making it easier for you to lose weight.

Enhances energy levels, stamina, and endurance: When you take Leanbean, you may find it easier to be productive during the day without experiencing fatigue. This supplement can also provide the energy boost you need for workouts.

Improves overall wellness: The Leanbean formula is rich in vitamins and minerals your body needs to function optimally. B vitamins also play a critical role in helping you lose weight.

How LeanBean Works – Formula Overview

The Leanbean formula combines the following natural ingredients:

  • Glucomannan
  • Vitamins B6 and B12
  • Choline
  • Chromium picolinate
  • Green bean coffee extract
  • Acai berry
  • Garcinia cambogia
  • Turmeric
  • Potassium chloride
  • Zinc

Glucomannan is one of the notable ingredients in Leanbean tablets included to help you lose weight. This absorptive dietary fiber from the konjac plant root can act as an energy booster, appetite suppressant, and source of healthy nutrition. Other ingredients in this formula that can curb food cravings include turmeric and potassium chloride.

The ingredients that can contribute to fat metabolism and weight loss include choline, acai berry, and garcinia cambogia. Chromium picolinate, green coffee bean extract, and potassium chloride contribute to healthy fat metabolism, weight loss, and digestion.

Zinc can help you maintain a healthy immune system. This nutrient promotes skin health and can help alleviate conditions such as acne. Turmeric and B vitamins can keep your energy levels high during the day.

Who Is This Weight Loss Supplement Best For?

Leanbean is one of the top natural phentermine alternatives for women of all ages. Women who are allergic to gluten or soy can take Leanbean tablets without experiencing reactions. If you don’t see the results you want from diet and exercise plans, this supplement might be the solution you need.

(Video) RX drugs without a prescription

If you are pregnant or breastfeeding, consult with your doctor before taking Leanbean.

Click Here for the Lowest Price on Leanbean

#5. PhenGold: Recommended OTC Adipex Alternative to Lose Weight Quickly

10 Best OTC Phentermine Alternatives (Adipex) Without Prescription (5)

PhenGold is one of the latest phentermine over-the-counter alternatives on the market and is known as a formidable fat burner. This supplement’s popularity is due to its effectiveness as a weight loss pill and a wide range of other potential health benefits, which include better digestion. When you take PhenGold, you might also notice relief from chronic anxiety, sleeplessness, and fatigue.

For best results, you should take three PhenGold tablets daily. Each bottle contains 90 tablets, which is a month’s supply.

PhenGold comes with a 100-day money-back guarantee.

The Benefits of Taking PhenGold

The PhenGold natural phentermine substitute offers several benefits:

Supports digestion: PhenGold is one of the natural weight loss supplements that offers exceptional digestion support. If you suffer from digestive problems that cause weight gain ― for example, acid reflux disease or irritable bowel syndrome ― consider PhenGold.

Curbs hunger: Some PhenGold ingredients are appetite suppressants, which canhelp you keep your dietary intake in check.

Improves energy and focus: PhenGold promises to provide the energy boost you need to go to the gym. This formula can also improve your focus and concentration.

Weight loss: The promised combination of digestive health improvements, no hunger pangs, and higher energy levels can result in significant weight loss. The PhenGold ingredients can also increase your metabolism and the conversion of body fat into energy.

How PhenGold Works – Formula Overview

The PhenGold formula consists of the following ingredients:

  • Cayenne pepper
  • L-tyrosine
  • L-theanine
  • Green tea leaf extract
  • Green coffee
  • Rhodiola rosea root
  • BioPerine® black pepper

Green tea leaf extract and L-theanine are the two ingredients in PhenGold that can support digestion. L-theanine is an amino acid that produces histamine, a neurotransmitter that plays a role in digestion and other processes, such as the body’s immune response and sleep-wake cycles. Green tea is rich in polyphenols, compounds that can support the digestive process.

The ingredients in the PhenGold formula that burn fat include cayenne pepper, green tea extract, green coffee, Rhodiola rosea, and BioPerine® black pepper. These compounds and extracts work together to increase your metabolism and help you lose weight.

Who Is This Weight Loss Supplement Best For?

PhenGold is the natural phentermine alternative for people who struggle with digestive issues and resulting weight gain. This supplement can also provide you with the energy you need to work out and helps keep you mentally sharp throughout the day.

You can expect the PhenGold formula to increase your metabolism and burn more body fat, with visible results within as little as four weeks.

Click Here for the Lowest Price on PhenGold

What Is Phentermine?

Phentermine is an FDA-approved drug that's one of the oldest prescription medications for losing weight. The drug’s brand names include Adipex-P, Lomaira, and Suprenza, and it falls under the anorexiant and CNS-stimulant drug classes.

Phentermine has a similar effect on the body as an amphetamine. This drug interacts with your central nervous system to increase your blood pressure and heart rate while suppressing your appetite.

Doctors typically only prescribe this medication to adult patients with a body mass index over 30 kg/m2, usually as a last resort to control weight gain. Patients should take this medication in addition to following a healthy diet and exercise plan.

Phentermine is not suitable for patients who are pregnant, breastfeeding, or suffering from health conditions such as high blood pressure, hyperthyroidism, glaucoma, heart disease, or stimulant allergies.

Taking phentermine can potentially result in adverse side effects, even in healthy patients, which is why some doctors are apprehensive about prescribing this medication.

High-quality phentermine over-the-counter alternatives offer the same benefits as phentermine and can help patients lose body weight. However, unlike phentermine, these dietary supplements generally have mild side effects, if any. These alternatives are also suitable for a broader patient profile, including those with underlying health concerns.

If you suffer from high blood pressure, type 2 diabetes, or any other health concern, consult with your doctor before taking weight loss supplements.

How We Ranked the Top OTC Phentermine Alternatives

A wide range of phentermine diet pills are available on the market, and selecting the right one for your needs and weight loss goals can be challenging. Each phentermine alternative has a unique formula and production process. The manufacturers of these products also don’t follow the same quality and production control standards, leaving the door open to safety and efficacy issues.

We considered various factors when we ranked the top phentermine over-the-counter alternatives for losing weight. These considerations give shoppers peace of mind that the products are trustworthy, effective, and suitable for consumption. The sections below discuss some of these supplement attributes.

Quality Ingredients

Ingredient quality is perhaps the most critical consideration when shopping for dietary supplements. When considering a product, you should research each ingredient in the formula and its interaction with the body.

In some cases, manufacturers add preservatives, colorants, and other potentially harmful compounds to their products. These ingredients can reduce the supplements’ effectiveness in helping consumers lose weight.

Ideally, a supplement should have an organic and all-natural formula with no synthetic compounds. Some manufacturers’ websites also provide additional information on how they source their ingredients, providing valuable insight into their product quality.

All the phentermine over-the-counter alternatives in this guide feature high-quality ingredients. Consumers who have difficulty losing weight can pick any of these supplements and expect to see results in a matter of weeks.


A diet pill’s dosage might not seem significant, but it can provide insight into how a specific supplement will fit your lifestyle and health requirements. For example, if you need phentermine alternatives that help you burn fat while preventing fatigue during the day, consider a product with a morning and afternoon formula.

Similarly, choose a supplement with separate daytime and nighttime formulas if you need an around-the-clock fat burner that supports your body’s sleep-wake cycle.

If you prefer a set-and-forget weight loss solution, a dosage of one tablet per day might be the ideal option for you. This review guide features high-end phentermine over-the-counter alternatives with varying dosages and usage recommendations, so you can choose one that is right for you.

(Video) How I Got Phentermine | My Advice

Customer Reviews

Customer reviews played a significant role in the creation of this review guide. People who used a weight loss product for several months can be valuable sources of information on the product’s efficacy and safety.

Suppose someone uses a phentermine over-the-counter alternative and experiences results within a few weeks with no adverse effects. In this case, they might naturally want to spread the word through customer reviews and help others on a weight loss journey. Similarly, if a consumer finds that a phentermine alternative doesn’t burn fat or that it causes allergies and other side effects, they will want to warn others.

Before buying phentermine diet pills, read customer reviews on third-party consumer sites and other independent platforms.


When choosing a product for ingestion, safety should come first. Unfortunately, weight loss supplements have a reputation for causing health issues, and you should always ensure that the formula you choose contains no harmful ingredients.

Allergies are a primary safety concern. If you are allergic to soy, dairy, or gluten, ensure that the supplement doesn’t contain these allergens. All the phentermine over-the-counter alternatives we review here are from reputable manufacturers who adhere to strict safety and quality standards.

To learn more about a supplement’s safety, consult your doctor, especially if you suffer from an underlying health condition.


Choosing the most affordable weight loss supplements makes financial sense, especially if you plan to take the pills over several months. However, price should never be your only buying consideration when it comes to phentermine substitutes.

Before putting a supplement to market, reputable manufacturers spend plenty of resources on research and development, which increases the retail price of their products. In other words, high-quality alternatives to phentermine are more expensive.

When you only shop for supplements in the lower price bracket, you risk buying a product that is ineffective, harmful to your health, or both. While the supplements in this review guide are not the most affordable, they will provide long-term health benefits.

Product Guarantee

High-quality alternatives to phentermine are generally expensive, and you don’t want to spend your hard-earned cash on a product that might not work for you. Choose a supplement with a money-back guarantee to ensure you don’t run any financial risks.

The money-back-guarantee period is significant, as these supplements can take up to two months before delivering results. Generally, a 60-day money-back guarantee provides enough time to find out if a supplement is a suitable option for you. Some products, such as PrimeShred and PhenGold, offer 100-day money-back guarantees.

Benefits of Choosing a Natural Alternative to Phentermine Diet Pills

How do phentermine natural alternatives compare to the prescription drug?

No Prescription Necessary

The most significant benefit of natural phentermine alternatives is that you don’t need a prescription to buy them, saving you valuable time and money. However, if you are unsure about the safety of a natural supplement, ask your doctor.

Effective Weight Loss Solution

According to some reviews by people who used phentermine and its natural alternatives, the supplements are more effective. If you want to lose weight quickly, one of the weight loss supplements might be a better option than the prescription drug.

Milder Side Effects

OTC phentermine supplements don’t interact with the brain and nervous system, which means the side effects from these products are generally mild. The vast majority of people who take these supplements usually don’t experience any adverse effects. Most ill effects of supplement intake generally result from sensitivity to caffeine.

Natural Ingredients

High-end phentermine supplement formulas contain natural, organic ingredients, eliminating exposure to synthetic and potentially harmful compounds.

Health Benefits

As a prescription drug, phentermine is primarily an appetite suppressant. On the other hand, the supplement alternatives to this drug can provide a comprehensive range of health benefits. These products boost metabolism, provide energy, maintain digestive health, and improve immune system health.

Risks and Side Effects of Prescription Phentermine Pills

As an anorectic, phentermine increases neurotransmitter levels in the brain to decrease feelings of hunger. When you take this drug regularly, you might build a tolerance to this effect and start feeling hungry again, increasing your risk of overeating.

Patients on phentermine often ask doctors to increase their dosage so they don’t start binging again, though this treatment is generally ineffective and potentially harmful.

Phentermine, as a stand-alone medication, is only suitable for short-term use. If doctors prescribe phentermine for longer-term use, it is usually only in combination with topiramate.

The common side effects of phentermine include:

  • Insomnia and other sleeping difficulties
  • Fatigue and irritability
  • Dizziness and headaches
  • Heart palpitations
  • Dry mouth
  • Skin flushing
  • Chronic fatigue
  • Nausea and vomiting
  • Constipation and other digestive issues

More severe, though rarer, side effects of phentermine include:

  • Cognitive impairment
  • Blood pressure increase
  • Metabolic acidosis, a body toxin build-up
  • Creatinine level increase
  • Vision problems

If you are pregnant, taking phentermine can be harmful to your fetus.

Common Ingredients Found in OTC Weight Loss Supplements

Each phentermine over-the-counter alternative has a unique formula and ingredient blend. However, most leading manufacturers add ingredients with clinically proven medical benefits to ensure that their products are as trustworthy and effective as possible.

In the sections below, we discuss common ingredients you can expect to find in phentermine alternatives and other weight loss pills. When shopping for a weight loss supplement, look for these ingredients.

Alpha-Lipoic Acid

Alpha-lipoic acids, such as α-Lacys Reset®, are popular ingredients in weight loss pills. This compound is known to be a fat burner and reduces the activity of AMP-activated protein kinase (AMPK), which is an enzyme in the brain's hypothalamus. As the AMPK enzyme becomes less active, your feelings of hunger should decrease.

The suppression of AMPK activity can also increase the number of calories that your body burns while resting. Other benefits of alpha-lipoic acids can include a lower risk of diabetes complications, skin antiaging effects, improved memory in older adults, and healthy nerve function.


Most OTC alternatives to phentermine have caffeine as an ingredient. This natural stimulant boosts your metabolism, increasing the number of calories your body burns per day. Caffeine is also an appetite suppressant that can curb binge eating.

Caffeine blocks adenosine, an inhibitory neurotransmitter, which can release feel-good chemicals such as norepinephrine and dopamine. This effect gives you energy and improves your focus.

The interaction between caffeine and the nervous system can increase the production of the hormone epinephrine, which breaks down dietary fat. Combining an increase in caffeine intake with exercise can help you achieve a negative energy balance, which results in significant weight loss.


Capsimax is a red chili pepper extract that targets several areas of weight loss. This ingredient can aid appetite control, the breakdown of stored fat, and thermogenesis. A daily dose of Capsimax can also increase resting energy expenditure, which is why some nighttime formulas feature this ingredient.

Capsimax uses an encapsulating technology that contains the spicy capsaicinoids from chili peppers to prevent any upsetting of your stomach. PhenQ is among the best phentermine alternatives that contain Capsimax powder.


L-carnitine is an organic metabolic compound that plays several roles in the body. This supplement can relieve various health conditions, including diabetes and heart disease.

(Video) Which WEIGHT LOSS MED works BEST? A Doctor looks at the DATA.

L-carnitine is integral to fat metabolism because it transports fats to the mitochondria. The cells' mitochondria convert fats into energy.

The intake of L-carnitine can reduce the visceral belly fat surrounding your organs. The supplement can also boost your metabolism and provide energy during workouts.

Other potential health benefits of this ingredient include immune system support and the breakdown of lactic acid build-up in the muscles.


Chromium, an essential nutrient, helps to regulate lipid, glucose, and carbohydrate metabolism. An optimal chromium intake can decrease body fat and increase lean body mass.

However, the average person’s regular dietary chromium intake is insufficient to derive these benefits. The body also doesn’t absorb chromium easily, so a supplementary intake of the nutrient might be crucial.

Select a phentermine alternative that contains chromium if you suffer from chronic anxiety, fatigue, or arteriosclerosis, as these conditions might indicate a chromium deficiency.

Green Tea

Green tea is rich in nutrients and offers many potential health benefits, from protection against oxidative stress to improving brain function. Weight loss is another significant potential benefit of this extract, which is why it is a common ingredient in phentermine OTC alternatives.

Green tea contains catechin, a flavonoid and a powerful antioxidant that can break down excess fat. This ingredient also contains caffeine, which can stimulate weight loss. Other potential health benefits of green tea include lowering cholesterol levels, improving cardiovascular function, and managing type 2 diabetes.

Guarana Extract

Guarana extract is a powder from the seeds of a Brazilian plant and a prominent ingredient in health supplements. This extract is rich in antioxidants and caffeine, which can boost your metabolism significantly.

Guarana can also suppress the genes that contribute to fat cell production and support the genes that slow fat cell production down.

Other potential health benefits of guarana include relief from chronic diarrhea and constipation, the promotion of cardiovascular health, and pain alleviation. This extract's antimicrobial and antioxidant properties can also have significant skin health benefits.

Cayenne Pepper

Cayenne pepper, a natural herb, can help you lose weight by speeding up your metabolism, curbing your appetite, and helping you burn calories. The weight loss properties of this herb have to do with its spiciness.

When you eat cayenne powder, your body temperature increases, and it starts cooling itself down. During this process, your body uses calories. One drawback of this ingredient is that some people develop a tolerance to its effects over time.

Cayenne powder offers various potential benefits, including the prevention of ulcers and high blood pressure.

Green Coffee

Unroasted coffee beans contain natural chemicals, such as caffeine and chlorogenic acid,which can help you lose weight. Chlorogenic acid is an organic antioxidant that can lower blood pressure and enhance mood.

This compound also produces alpha-glucosidase, an enzyme that can break down carbohydrates. The result is a lower absorption of glucose and carbs during digestion.

Other functions of chlorogenic acids can include protecting against beta-amyloid proteins, which are the primary cause of Alzheimer’s disease. The compound facilitates the manufacturing of glutathione and vitamins, which can protect the body against inflammation.

Related Content:

  • Best Probiotics: Top 5 Gut Health Supplements of 2022
  • Best Meal Replacement Shakes: Top 8 Weight Loss Shakes and Meal Supplement Powders of 2022
  • Best Fat Burner Pills: Top 5 Fat Burning Supplements of 2022

Where to Buy Real Phentermine (Adipex-P)

Real phentermine is a controlled substance, and you cannot buy this medication over the counter or online without a prescription. A doctor will only prescribe this drug after consultation and thorough examination to ensure that you are an eligible candidate for the treatment. You are only eligible for a phentermine treatment if you:

  • Struggle to lose weight with diet and exercise alone
  • Have no underlying health concerns that might result in side effects

After prescribing phentermine, your doctor will schedule follow-up visits to monitor your progress. Once you reach your weight loss goals, your doctor will likely take you off the medication.

When doing an online search for Adipex, you will find several websites that sell the drug online. However, these websites are likely scams or selling the medication illegally.

How Long Does It Take for Natural Diet Pills to Help You Lose Weight?

How quickly can you expect to see results after you start taking phentermine substitutes? You can expect visible effects within two weeks if you:

  • Select a high-quality supplement
  • Follow the recommended dosage and usage instructions
  • Combine the supplement with a healthy diet and exercise routine
  • Drink enough water every day

Keep in mind that everyone has a unique reaction to phentermine alternatives. Your body might take a month or two before adjusting to the new supplement, in which case it might take longer before you see noticeable results.

Things To Consider Before You Buy an OTC Phentermine Alternative

Your safety should be the first consideration when you buy substitute-phentermine supplements. If you are pregnant, breastfeeding, or under 18, you should not buy weight loss pills.

You also need to consider your specific requirements. For example, if you are doing high-intensity weight training, consider a supplement such as PrimeShred, which has a distinctive formula to support muscle growth. If you have a medical condition, such as an endocrine gland malfunction, that makes you susceptible to hormonal imbalances, consider the Leanbean supplement.

Frequently Asked Questions on Phentermine Replacements

How long can you take phentermine?

Following your doctor’s recommendations is critical when taking phentermine to mitigate your risk of side effects. Most doctors will only prescribe this medication for up to 12 weeks to prevent adverse effects such as headaches, nausea, anxiety, heart palpitations, and increased blood pressure. The relatively short durations of these treatments also protects patients against addiction.

How much weight can you lose on phentermine in 3 months?

Clinical studies suggest that losing 5% or more of your body weight during three-month phentermine treatment is possible. The factors determining how much weight you can lose on phentermine include your dosage, your weight before starting the treatment, and the lifestyle changes you make during the weight loss process.

Is Phentermine a prescription drug?

Yes. Phentermine is a Schedule IV drug, which means it is a controlled substance that can potentially be habit-forming and cause patients to undergo withdrawal. Consequently, phentermine is a prescription drug. Patients are eligible for a phentermine prescription only if they:

  • Have a BMI of 27 to 30
  • Have struggled to lose weight through conventional methods

Who should not use phentermine weight loss pills?

Patients suffering from the following health conditions should not take phentermine:

  • Cardiovascular disease
  • High blood pressure
  • Stimulant allergies
  • Hyperthyroidism
  • Glaucoma

If you suffer from chronic anxiety or have a history of drug abuse, you should not take phentermine. Women who are pregnant or breastfeeding are not eligible candidates for phentermine treatment.

How much do diet pills like phentermine cost?

A month’s supply of phentermine costs around $40. Phentermine alternatives are generally more expensive than the prescription drug itself. Look for coupon codes or combination discounts to make your alternative supplement purchases more affordable.

Summary of the Top Recommended Alternatives to Phentermine Weight Loss Pills

  • PhenQ: Best OTC phentermine alternative overall
  • Phen24: Great metabolism booster for 24-hour fat burning
  • PrimeShred: Good men’s diet pills for burning fat
  • Leanbean: Best adipex alternative for women
  • PhenGold: Best alternative to anti-obesity medication
  • Instant Knockout: Recommended for belly fat
  • PhenQ PM: Highest quality nighttime fat burner
  • Trimtone: Top-notch diet pills for women over 50
  • CalmLean: Best stimulant-free fat burner for men
  • Keto Charge: Best for keto diet and intermittent fasting

*This article is provided by an advertiser. Statements made are not meant to offer medical advice nor to diagnose any condition. Any studies cited here may be preliminary, and may or may not be peer reviewed, and may or may not have sufficient participants to be statistically relevant. Anecdotal accounts should not be taken as scientific results. Products discussed in this article are not designed to diagnose, treat, prevent, or cure any disease. The FDA does not evaluate dietary supplements. Consult your doctor about possible interactions, allergies, and if you are considering using a natural and/or dietary supplements for any condition. Individual results will vary.


What other weight loss pills besides phentermine? ›

Six weight-loss drugs have been approved by the U.S. Food and Drug Administration (FDA) for long-term use:
  • Bupropion-naltrexone (Contrave)
  • Liraglutide (Saxenda)
  • Orlistat (Xenical, Alli)
  • Phentermine-topiramate (Qsymia)
  • Semaglutide (Wegovy)
  • Setmelanotide (Imcivree)
Oct 29, 2022

How to take phentermine 37.5 for best results? ›

  1. Adults and children 17 years of age and older— Lomaira™: One tablet three times a day, taken 30 minutes before meals. Phentermine: 18.75 to 37.5 milligrams (mg) once a day, taken before breakfast or 1 to 2 hours after breakfast.
  2. Children 16 years of age and younger—Use is not recommended.
Feb 1, 2023

What are the different brands of phentermine? ›

US Brand Name
  • Adipex.
  • Adipex-P.
  • Atti-Plex P.
  • Fastin.
  • Ionamin.
  • Lomaira.
  • Phentercot.
  • Phentride.
Feb 1, 2023

How long does it take to get a tolerance break on phentermine? ›

Out of 148 subjects, 66% who completed at least 3 months of treatment developed tolerance to the weight-reducing effect of 30 mg phentermine at any given time point during follow-up: early tolerance (first 3 months) occurred in 25%, whereas late tolerance (4–6 months) was observed in 41%.

Is there a non prescription substitute for phentermine? ›

Leanbean: Natural Diet Pills Available Without a Prescription. Leanbean is among the best over-the-counter diet pills for women and a high-quality alternative to phentermine prescription medication. This all-natural formula is compatible with female physiology and can promote healthy hormone production.

What is the most successful weight loss pill? ›

What is the most effective weight loss pill available? Phentermine is one of the most effective weight loss medications. However, it is only indicated for short-term use. The GLP-1 agonists liraglutide (Saxenda) and semaglutide (Wegovy) are also approved for weight loss and have been shown to be particularly effective.

Can you lose 20 pounds in a month on phentermine? ›

In general, phentermine can help you lose 3-7% of your body weight. You can expect to lose anywhere from 3 lbs to 5 lbs a month on phentermine. Remember that phentermine is for short-term use only (a few weeks).

Can an online doctor prescribe adipex? ›

In the US and many other countries, this drug is considered a Schedule IV controlled substance. It is illegal to purchase phentermine without a prescription. While you can get a prescription through telemedicine, most physicians require you to have an in-person visit.

What are the requirements to get Adipex? ›

The drug is approved for use in adults with a body mass index (BMI) of 30 or greater (obese) or adults with a BMI of 27 or greater (overweight) who have at least one weight-related condition such as high blood pressure (hypertension), type 2 diabetes, or high cholesterol (dyslipidemia).

What is the closest thing to phentermine? ›

Adipex and Lomaira are two of the best known phentermine alternatives. Both are available on the market and can be purchased online. In the United States, Adipex is the most common brand of phentermine diet pills.

What is a natural version of phentermine? ›

Green Coffee and Tea Extracts Energy sources that stimulate thermogenesis and suppress appetite. Grain of Paradise is a natural stimulant of thermogenesis. Glucomannan is an ingredient that helps users feel full for a longer period.

What is the strongest phentermine pill? ›

37.5 mg is the highest dosage – since phentermine can only be taken for a limited time, this means that patients get the maximum benefits in the minimum time. Phentermine tablets are only available in 37.5 mg, and more patients are prescribed tablets than capsules.

What happens if phentermine 37.5 doesn't work anymore? ›

However, if phentermine doesn't work, stops working, or has an intolerable side-effect, you should ask your physician to switch to a different weight loss medicine. There are lots of options. Some people have to take other medications which cause weight-gain; other patients have genetic obesity.

Can you build a resistance to phentermine? ›

However, you may build a tolerance to the appetite-suppressing effects of phentermine within a few weeks. If that happens, speak with the healthcare professional who prescribed it. Phentermine is thought to decrease your appetite by increasing neurotransmitter levels in your brain.

How long does it take phentermine to start suppressing appetite? ›

You will likely notice a decrease in appetite within three to five days of taking the medication. However, it may take a week or two to see the full effects of the medication on appetite suppression and weight loss.

Does Canada sell phentermine over the counter? ›

Often sold under the brand name Adipex, Phentermine is one of the most popular weight loss drugs in the world. However, although Adipex is available via a doctor's prescription in the US, Canada, and Australia, it is not legally available in many other countries of the world.

How much weight can I lose with PhenQ? ›

Reviewers commonly describe losing 5–10 pounds per month when taking PhenQ pills. However, your results will vary depending on your diet, exercise routine, and other factors such as hormone levels. Some individual ingredients have had their effects on body weight measured.

What pill does weight loss Kardashian take? ›

The drug is garnering a lot of attention as a way to lose weight on social media platforms such as TikTok. The story so far: The dramatic weight loss of Kim and Khloe Kardashian and other celebrities has been rumoured to be the work of an injectable drug, Ozempic, that's been called 'Hollywood's worst kept secret'.

What is the new breakthrough weight loss pill? ›

The first new highly effective drug, semaglutide, sold as Wegovy by Novo Nordisk, won regulators' approval for obesity in mid-2021. A few months ago, Wegovy was approved for use by adolescents, too.

What are the famous TikTok weight loss pills? ›

As a result, Ozempic has been touted on the Internet as a miracle diet drug. On TikTok, the hashtag #Ozempic already has over 600 million views and counting. Even Twitter's new boss, the billionaire Elon Musk, has credited Ozempic - alongside a similar drug, Wegovy - as one of the reasons he shed 13 kg.

How long is too long on phentermine? ›

Phentermine should only be used for short-term use (less than 12 weeks at a time) to help with weight loss.

How fast do you lose weight on Adipex? ›

On average, the expected weight loss with Adipex is five percent of your starting weight or more. Over 12 weeks, it's possible to lose as much as 10 percent of your initial body weight. If you start off weighing 200 lbs, you can expect an Adipex weight loss total of 10 to 20 lbs within the first three months.

What is the average monthly weight loss on adipex? ›

95% of patients who use Phentermine experience positive results, with an average weight loss between 4-8 pounds per month.

Will a Teladoc prescribe phentermine? ›

Teladoc doctors do not issue prescriptions for substances controlled by any federal or state agency or other drugs that may be harmful because of their potential for abuse.

Is it illegal to buy phentermine? ›

Federal law prohibits buying controlled substances such as narcotic pain relievers (e.g., OxyContin®, Vicodin®), sedatives (e.g., Valium®, Xanax®, Ambien®), stimulants (e.g., phentermine, phendimetrazine, Adderall®, Ritalin®) and anabolic steroids (e.g., Winstrol®, Equipoise®) without a valid prescription from your ...

What is PhenQ? ›

PhenQ is a cutting-edge fat-burning supplement that uses proven science and research to help you lose weight. The active ingredients in PhenQ are known to boost your metabolism, suppress your appetite, and accelerate the loss of stored body fat.

What is an over the counter version of adipex? ›

Trimtone: Strong Adipex Alternative for Boosting Metabolism. Trimtone is a natural workout aid that helps women burn fat and reduce their appetite. The formula stimulates thermogenesis, the process your body uses to convert stored fat into energy.

How much is adipex at Walgreens? ›

Average 12 Month Prices for Adipex-P
PharmacyAdipex-P Retail PriceAdipex-P SingleCare Price
Kroger Pharmacy$35.04$11.49
Albertsons Pharmacy$38.33$14.99
Rite Aid Pharmacy$45.87$16.06
2 more rows

Which is better Adderall or phentermine? ›

Phentermine is the better choice for you if your goal is to shed weight. It is a viable treatment for those suffering from significant overweight. Whereas Adderall is the better choice for helping you to maximize your focus and cognition.

Which is better phentermine or adipex? ›

Adipex-P has an average rating of 8.9 out of 10 from a total of 608 ratings on Drugs.com. 86% of reviewers reported a positive effect, while 4% reported a negative effect. Phentermine has an average rating of 8.7 out of 10 from a total of 2985 ratings on Drugs.com.

How much does PhenQ cost? ›

Here is the price breakdown for the PhenQ supplement: One bottle: $69.99. Three bottles: $139.99. Five bottles: $209.99.

How to get adipex for weight loss? ›

Buying Adipex at local stores will ask you for a prescription, which is why most people prefer to buy Adipex online. The sale of phentermine drugs online has increased over the last couple of years and some of them pass through the prescription test who don't really need the diet pills.

Is phentermine 37.5 the same as Adipex? ›

Adipex-P is a longer-acting form of phentermine. It's available as 37.5 mg capsules and tablets that are taken once per day. On the other hand, Lomaira is a shorter-acting form of phentermine that comes as 8 mg tablets taken three times per day.

Is benzphetamine stronger than phentermine? ›

Phentermine is stronger than Benzphetamine when it comes to weight loss, so the dosage of phentermine is slightly lesser than what doctors prescribe Benzphetamine to their patients. The dosages aren't always different, Benzphetamine dosage starts from 5mg and reaches up to 50 mg/day.

Is there a generic phentermine? ›

Phentermine is a generic drug prescribed short term to help certain adults manage body weight. It's available in these oral forms: tablet, capsule, and disintegrating tablet. It comes as the brand-name drugs Adipex-P and Lomaira.

What to do when you stop taking phentermine? ›

If you suddenly stop using this medication, you may have withdrawal symptoms (such as depression, severe tiredness). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used phentermine for a long time or in high doses.

What happens if you take phentermine for more than 3 months? ›


Longer-term use, >12 months, was associated with significantly more weight loss (7.4%) than a duration of use < 3months and a risk of CVD or death comparable with that associated with a shorter-term use.

Can phentermine cause permanent damage? ›

Phentermine may increase your thyroid activity. This may raise your thyroid levels even further. For people with glaucoma: This drug may increase your eye pressure even more. This may cause permanent damage to your vision.

What disqualifies you from taking phentermine? ›

Heart or blood vessel disease (eg, coronary artery disease), history of or. Hypertension (high blood pressure) that is not controlled, history of or. Hyperthyroidism (overactive thyroid) or. Stroke, history of—Should not be used in patients with these conditions.

What supplements help phentermine? ›

Replenish Depleted Nutrients
  • Biotin. ...
  • Calcium. ...
  • L-Carnitine. ...
  • Vitamin A. ...
  • Vitamin B12. ...
  • Vitamin D. ...
  • Vitamin E.

How to get more energy from phentermine? ›

Lethargy and fatigue can be alleviated by drinking enough water when taking Phentermine 37.5. The body's tendency to feel intellectually lethargic will disappear if you drink a maximum of 8-9 glasses of water daily.

Does coffee make phentermine less effective? ›

Both phentermine and caffeine are stimulants. They both can cause insomnia, increased heart rate and jitteriness. It is likely that if you use caffeine while taking phentermine these side effects will be increased. It is recommended that you limited you caffeine use while taking phentermine.

What happens if you don't eat while taking phentermine? ›

Since phentermine is an appetite suppressant, it can be tempting to skip meals. It is important to avoid doing so, as skipping meals can slow down your metabolism, making it hard to lose weight in the long run.

Can I eat bananas on phentermine? ›

Foods - Eating healthy food such as broccoli, carrots, cucumbers, bananas, and almonds increases Phentermine's absorption and should be taken. Avoid food rich in sugars and butter as they increase the excretion of Phentermine from the system.

What is the best substitute for phentermine? ›

Adipex and Lomaira are two of the best known phentermine alternatives. Both are available on the market and can be purchased online. In the United States, Adipex is the most common brand of phentermine diet pills.

How to get mounjaro for weight loss? ›

The medication can be picked up at any pharmacy that carries it (just like any other medication), and it does not have to be administered by a healthcare professional. The injection itself is easy to do but may cause some minimal pain or discomfort.


1. Phentermine 2019 | How to get it Quick Weightloss Drug
(Robyn Bryce)
2. FDA approves potential game-changer drug for weight loss, but it comes with a hefty price tag
(CBS Mornings)
4. Phentermine For Weight Loss | Side Effects & Best Practices
(Pharmacist Conversations)
5. STOP Taking Phentermine (It Doesn't Work)
(Dr. Westin Childs)
6. PHENTERMINE | Where I get phentermine


Top Articles
Latest Posts
Article information

Author: Ouida Strosin DO

Last Updated: 06/18/2023

Views: 6522

Rating: 4.6 / 5 (56 voted)

Reviews: 95% of readers found this page helpful

Author information

Name: Ouida Strosin DO

Birthday: 1995-04-27

Address: Suite 927 930 Kilback Radial, Candidaville, TN 87795

Phone: +8561498978366

Job: Legacy Manufacturing Specialist

Hobby: Singing, Mountain biking, Water sports, Water sports, Taxidermy, Polo, Pet

Introduction: My name is Ouida Strosin DO, I am a precious, combative, spotless, modern, spotless, beautiful, precious person who loves writing and wants to share my knowledge and understanding with you.